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High-resolution anoscopy is a technique similar to colposcopy that has been adapted to evaluate the anal epithelium. HSIL also shows overexpression of certain biomarkers, including p Like warts, the goal of treatment is to get rid of the precancerous lesions. After the intra-anal area is thoroughly examined with the microscope and biopsies are obtained, the anoscope is removed. HRA can be performed comfortably in the physician's office.